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Experimental and computational Φ-value analysis of two-state helical proteins has shown that definite interactions among helix-forming segments build up in the transition state ensemble, but this type of analysis is not applicable to downhill folders.
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Nuclear extract EMSA showed definite interaction between the PRE and both PC12 and U937 extracts.
This study supports the earlier findings of CALGB 9344 [ 5], which indicated benefit from the addition of taxanes, although the CALGB 9344 study suggested a definite interaction between ER status and benefit from taxanes.
As shown in Figure 7b, beyond the equilibrium distance of the potential well ( <img src="http://journals.plos.org/plosone/article/asset?id=info?doi/10.1371/journal.pone.0018081.e124.PNG" class= inline-graphic"/> ), the colored gradient outlines the range for which element-element interactions are definite, but cell-cell neighboring relationships could be considered uncertain.
IPA is a commercial knowledgebase that contains approximately 3,000,000 biological and chemical interactions with definite scientific evidence.
Phase analysis and oxidation state study of the composite revealed a definite chemical interaction between the core and shell.
The formation of supramolecular assembly becomes effective at a lower surfactant concentration with increasing dextran size as a consequence of definite dye surfactant interaction and could pave a facile strategy for designing hierarchical superstructures.
The ability and remarkable specificity of AP2C3 to channel the pleiotropic MPK3 and MPK6 pathway towards the stomata development may rely not only on its stomata lineage specific expression, but also on its definite docking interaction with the MAPKs, as well as its particular localization within the cell.
Although there might also be some concern about the increased risk of bleeding, the critical concentration at which bleeding occurs is much higher than the recommended dose, and there has been no clinical evidence of a definite, direct interaction between rhTM administration and increased risk of bleeding-related complications in obstetric DIC [ 30].
With the limitations in the study of solely predicted gene interactions, definite conclusions about the nature of the resistant response to F. virguliforme infection cannot yet be made.
As the structures of more DNA-protein complexes were determined it became apparent that there were definite preferences for interactions between particular amino acids and base pairs, and that those preferences might vary depending on the class of TF.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com