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In total, 24% of those with CHADS2=0 and 81% of those with a CHADS2=1 were reclassified as having a definite indication for OAC (CHA2DS2-VASc score ≥2).
A definite indication for a putative role of IxACs as anticomplement therapy must await tests in animal models of candidate diseases.
Our finding of a very high HIV-related case fatality rate in severely anaemic children suggests that it is now appropriate to consider adding severe anaemia to the criteria for stage IV disease ie a definite indication for commencing ART in the WHO paediatric HIV staging system.
Structural change is a definite indication for urate-lowering therapy.
Predicted difficult airway is a definite indication for awake intubation and spontaneous ventilation.
Patients were ineligible if they had a definite indication for, or contraindication to, either of the active study treatments or had a definite indication for long-term insulin therapy.
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Lynette Denny, a gynaecology professor at the University of Cape Town, told the Times: "There are definite indications for a caesarean section, which can be life saving for both mother and child.
In the absence of definite indications for intervention, we must do what we can to support clinical situations remaining normal.
Early-stage disease and T3N1 NSCLC are considered definite indications for surgery.
In our retrospective study, there was no predefined protocol regarding definite indications for rhTM treatment.
The electronic support tools included a summary of antibiotic prescribing recommendations, a printable patient information sheet, a summary of research evidence concerning no antibiotic or delayed antibiotic prescribing strategies, information on the definite indications for antibiotic prescription, as well as information and evidence on the risks from non-prescribing.
More suggestions(16)
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com