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Within the Mendip Hills AONB, good evidence exists for 286 definite examples of round barrows, including the Priddy Nine Barrows and Ashen Hill Barrow Cemeteries.
In contrast, definite examples of competence pheromones have not yet been reported in Gram-negative bacteria, although quorum-sensing pheromones [N-acyl-homoserine lactones (AHLs) and autoinducers (AIs)] possibly influence competence development indirectly [16].
Overall, we suspect that stop-loss mutations of uORFs are likely to represent an under-recognized class of hypomorphic mutations, although a search of the Human Gene Mutation Database (HGMD) (see Materials and Methods) did not yield any definite examples.
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Thus Peter Singer's exhortations to us to take up the moral point of view (see e.g. Practical Ethics 10 11[33]) give us perhaps the most definite example available of an external reasons theory in contemporary moral philosophy but are also one of the least clearly-explained or justified parts of Singer's position.
Making a case for David Bowie's genius has to be a definite example of Stating The Bleeding.
Yet, so far a definite example for such vesicular control of fusion pore expansion was still missing.
If the replication model is correct, then C. albicans and C. dubliniensis represent the first examples of GC content evolution driven by replicative errors, a mechanism proposed long ago by Wolfe et al. (1989) for which no definite example has so far been found.
We defined "probable" cases as those with a relevant medical code but with only one of the further "definite" case criteria for example, a record of a referral or a confirmatory liver function test result.
If "human being" means something definite, for example, "two-footed animal" (Aristotle's dummy definition), then, Aristotle concludes, it is impossible that the same thing be a human being and not be a human being.
"It's a very moving, wonderful story, as indeed is his book," he says, "but we always have to realise in a single-case report there are factors that may be important that aren't necessarily being examined and therefore we can't conclude anything definite – for example, that the baclofen high dose made this remarkable change in him.
(Other definite or likely examples of Gould's work on view now include a four-drawer chest at the Jeremiah Lee Mansion in Marblehead, Mass., and a bombé-front desk in Gallery 103 at the Philadelphia Museum of Art).
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com