At BL, the VEs with or without spinal inflammation in MRI showed similar proportions of definite radiographic damage at BL (17.6% versus 15.6%, respectively; P > 0.05).
Compared with other heavy-metal compounds such as manganese chloride, zinc chloride, mercuric chloride, and lead chloride, CdCl2 could increase the levels of Grp78, ATF4, and the phosphorylated form of eIF2α more markedly without definite cellular damage.
The Fisher exact test was used for comparison between different subgroups such as those with VEs and without spinal inflammation or with and without definite radiographic damage and progression.
We encountered large variability of the plasma levels of NfH, which can be noted in the range of values in Table 3. Occasional values in one patient were high without an apparent clinical correlate and occasional patients with definite brain damage did not have measurable plasma levels of NfH.
Our results were similar to those found using healthy volunteers [ 31, 32], but differed from those using nerve injured patients [ 33, 34], where a high degree of reliability was established, suggesting that monofilaments are most reliable for those with definite nerve damage.
Economic return is definite, whereas environmental damage is only possible.
A neurological report carried out soon afterwards found no definite evidence of brain damage: "LSD made him quite aggressive, which he realises," it said.
The medical people were definite there was no damage to my heart, so I once I got the OK I could touch base again".
Each area of the brain was graded on a scale of 0 to 4. The following criteria were used to assign scores for each region: 0 = no pathology; 1 = no tissue destruction with minimal inflammation; 2 = early tissue destruction and moderate inflammation; 3 = definite tissue destruction (parenchymal damage, cell death, neurophagia, neuronal vacuolation); 4 = necrosis (complete loss of tissue elements).
The aim of an HTO is to delay the progress of a disease already started, with the option of later conversion if needed, while an arthroplasty can be viewed as a "definite" treatment of a damaged joint or part thereof.
At their comeback shows at the Roundhouse, there were fans complaining afterwards that their ears hurt, it was so loud, a definite warning sign of hearing damage.
