The Touchet beds are one element in a chain of evidence which helped identify and define the progression of the Missoula Floods, which occurred around 16,450 to 13,750 years BCE.
To define the progression of DPN in this model, we performed a detailed phenotypic characterization of Ins2Akita/+ mice.
A key outstanding issue when considering using Lewy body pathology to define the progression of PD is regarding whether the Lewy body itself is harmful or protective.
Meanwhile, clinical manifestations of a chronic HSV infection (HSV-1 or HSV-2) among HIV/AIDS patients have been regarded by the World Health Organization (WHO) as an important presentation defining the disease progression of HIV/AIDS [ 7].
Although the identification of putative biomarkers based on their individual expression patterns will continue to represent a fundamental research tool, there is a need to explore methodologies not only for improving prognostic performance, but also for augmenting our understanding of processes defining the emergence and progression of HF after MI.
Individual blood biomarkers have been unsuccessful in defining the disease pathology, progression and thus diagnosis.
Our data indicate that plasma determination of fibrinogen and C-RP might have a clinical implication in defining the process of progression of PAD in T2D population.
The latter framework allowed detailed investigation of spatiotemporal transport of fluid between the vasculature, cerebrospinal fluid and brain parenchyma, and exploration of hypotheses defining the initiation and progression of acute and chronic hydrocephalus.
While defining the probability of progression of early lesions to full-blown cancer is a major challenge in cancer research, it must be emphasized that today most patients are diagnosed when their disease is at an advanced, metastatic stage (reviewed in Valastyan and Weinberg 2011).
Defining the mechanisms underlying the progression of DCIS has been the subject of recent intense study.
This is one way we can define the incidence, progression, regression and disappearance probabilities.
