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If he is indeed defining the course and strategy of the uprising, the possibility that his personal intentions will fall short of the more radical calls from many of his supporters becomes problematic (for him).
The impact will be defining the course of the peace negotiations between Israel and the Palestinian Authority, but there are also questions concerning Hamas, Egypt and, for obvious reasons, Turkey.
It's a fascinating and pulse-pounding time in human history, a time in which strong women as well as men were furiously defining the course of events for millennia to come.
It is becoming clear that although polyQ tracts themselves are toxic, the sequence and structure of the proteins carrying the polyQ tracts have important roles in defining the course and specificity of the disease.
Sex differences can have major contributions in defining the course of these regulatory steps.
Ceruloplasmin has been implicated in global SLE, but was not found to be an effective metric for defining the course of LN in pediatric patients.
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And in defining the courses as largely Western, the colleges -- including Clemson University in South Carolina and the University of Wisconsin at Milwaukee -- are perhaps writing the next chapter in the two-decade-old debate over which works should be considered great, a fierce cultural discussion that shows no signs of abating.
However, from the point of view of biomechanics, and particularly directions defining the courses of muscle fibres and location of insertions to the mandible, its meaning and role are generally insignificant in issues concerning biostatic balance of the mastication organ.
It was not his personal sexual proclivities that has defined the course of his public career.
The new president will define the course Brazil will take in the next four years.
In the Trump Presidency, as in all Administrations, there will be political fights that define the course of events.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com