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It is possible that these proteins participate in similar activities, with certain residues in the cavity defining specificity of the ligand.
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The program calculates the theoretical masses of peptides obtained from in silico digestion taking into consideration the defined specificity of trypsin.
Thornberry NA, Rano TA, Peterson EP, Rasper DM, Timkey T, Garcia-Calvo M et al. A combinatorial approach defines specificities of members of the caspase family and granzyme B. Functional relationships established for key mediators of apoptosis.
We defined specificity as the proportion of irrelevant articles not retrieved by the search filters.
In a 1996 landmark achievement, Altman and co-workers [7] generated fluorescence labeled, peptide-MHC multimers of defined specificity (generally known in the field of T cell immunology as "MHC tetramers") and demonstrated their ability to stain specific T cells.
Defining the specificity of the human T cell repertoire, and identifying factors that govern early responses may allow for development of novel diagnostics and therapeutics for both invasive and allergic Aspergillus diseases.
The 900 bp-long sequence could potentially encode part of the mechanism defining the specificity of the vtx2-phages for EAggEC strains, being directly involved in the phage-bacterium interaction.
Based on this observation, we could suggest that although the consensus (NxxAQxxHR) sequence defines the specificity of the target DNA binding, auxiliary residues, as G70 in the case of FlbB, modulate the efficiency of the interaction.
This enzyme will define the specificity of the response favoring the formation of MR-MC complex over MR-GC complex.
The dissociation curve analysis was used to define the specificity of the products by the presence of a single dissociation peak on the thermal melting curve.
The various phosphorylated tyrosine residues of the receptor serve as binding sites for different secondary signaling molecules and define the specificity of the signaling pathway.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com