Yeast TERRA was reported to form RNA/DNA hybrids negatively regulating telomerase-dependent telomere elongation; however, the possible role of TelRNA/TERRA in defining telomeric silencing has not yet been addressed (Azzalin et al, 2007; Luke et al, 2008).
The rate of such long hesitation events, defined as silences longer than approximately one second, is used to detect the disease.
cAMP 20% WT [81] BW Ballesteros Weinstein numbering, WT wild type aMutation causing decrease of the receptor constitutive activity is defined as silencing.
One other interesting point about heterochromatin is known as positive-effect variegation, which is defined as silencing of a normally expressed gene when it is brought into juxtaposition with pericentric heterochromatin (Cryderman et al., 1998).
Hits were defined if silencing satisfied three conditions: (1) it increased the total amount of p-EGFR in endosomes and (2) increased the mean amount of p-EGFR per endosome, and (3) the phenotype was observed with at least two siRNAs per gene.
Thus, we defined non-silenced genes as silencing activity<0.5, moderately silenced genes as 0.5<silencing andivity<1.0, and highly silenced genes as silencing activity>1.0.
Perhaps in time, rather than a defining hiatus, the silence that fell upon Bush between the mid-1990s and mid-noughties will come to be seen as a healthy pause, a reinvigorating gap, between two imperial phases.
They also go a long way in defining the current silence on the issue.
To be admitted to the course, students must demonstrate in an interview the extent of their reticence, defined as "chronic silence due to a fear of foolishness".
If July was defined by discomfiting silence and August by incendiary rhetoric, then September has been all about quiet diplomacy in the N.B.A. labor war.
