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Australian guidelines for identifying those at risk are currently based on a confusing mix of rules and prescribing criteria for defining risk factor thresholds for 'high blood pressure' or 'high cholesterol' [ 9- 12].
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Among migraineurs, defining risk factors for CM, or for the progression of episodic migraine to CM, is an issue of scientific and public health interest [6].
Defining risk factors associated with the development of ARDS in patients with an infectious disease is challenging because virulence factors of different pathogens have been implicated in causing lung damage.
Defining risk factors leading to comorbidities is important in psoriasis.
Further investigations are needed for defining risk factors and molecular pathways of HCC from HCA.
Much effort has gone into defining risk factors for the development and progression of Alzheimer's dementia, as well as to identify biological markers for the disease.
In defining risk factors for primary transmission of Marburg virus in Durba/Watsa, our study helps orient the hunt for the reservoir for the filoviruses.
Although some uniformity would be desirable, screening based on risk factors would involve defining risk factors in the particular population and not just importing from a possibly irrelevant or unrepresentative population.
However, identification of risk alleles in modifier genes and understanding their contribution to phenotypic variation may open the possibility of defining risk factors early in life, allowing more accurate diagnosis in due time and providing better prediction of disease course.
Defining risk factors associated with the development of ALI in patients with infectious pneumonia is challenging because virulence factors of different pathogens have been implicated in causing lung damage [ 12, 13].
23, 25 This association reinforces the need for early detection of metabolic syndrome prior to transplantation in order to establish therapeutic interventions to correct metabolic syndrome defining risk factors.
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