Cumulative incidence was defined as a change from no heavy menstrual bleeding in the age-defining questionnaire to heavy menstrual bleeding in at least one of the questionnaires during the analysis time frame.
Resolution was defined as a change from heavy menstrual bleeding in the age-defining questionnaire to no heavy menstrual bleeding for the whole of the analysis time frame (i.e. without recurrence).
The analyses for resolution were also repeated, stratified separately for each of the characteristics of interference with life, skipped periods and 'cycle too variable to say', and with status defined by responses in the age-defining questionnaires.
Women contributed to the denominator population ('women at risk of heavy menstrual bleeding') for each time period of 6 months, where they started in the 'age-defining' questionnaire with no heavy menstrual bleeding, and their status at the end of each 6 months was dichotomised into 'heavy menstrual bleeding' yes or no.
Women contributed to the denominator population ('women at risk of resolution of heavy menstrual bleeding') for each time period of 6 months if they started in the 'age-defining' questionnaire with heavy menstrual bleeding, and their status at the end of each 6 months was dichotomised into 'resolution of heavy menstrual bleeding' yes or no.
Table 2 shows the constructs used in defining the questionnaire for the roles approach.
Table 1 lists the constructs used when defining the questionnaire to collect data related to the process approach.
Clinical directives given by MP included defining the questionnaire and study objectives, making final decisions and data interpretation.
While "work" is not defined, the questionnaire stipulates that pay may be for cash or in kind.
Due to the simplicity of the questions, we defined the questionnaire based on our own perceptions about what is important in order to capture the developer knowledge on the subject.
Statistically important positive correlations were observed between all QLCCDQ dimensions defined by questionnaire's subscales [Table 6].
