To date, research has generally defined promising medical school entrants in negative terms that is, those who are least likely to fail undergraduate or postgraduate examinations or face future professional disciplinary action.
Several investigators have tried to overcome the limitations of these 'first generation' signatures by focusing on the BC microenvironment or immune response (or both) to define promising 'second generation' prognostic signatures (Table 1) [ 19].
We believe that the pan-cancer subgroups defined here are promising stratifications of tumors for deciphering the underlying mechanisms of cancer deeply.
Did he find it ironic that his defining hit was about promising never to let people down or desert them, and that's exactly what he did?
Moreover, a Bayesian form of this new model is constructed, and an extension of this model, the Confidence Index (CI), is defined and may be promising for applications.
The assessment process took into account factors and information that could impact the success of measures if they were applied in different European environments, and drew conclusions on a list of measures defined as recommended and promising.
The combination of genetic and 3D coculture approaches in future studies appears promising to define further isoform-specific effects, as reported for laminin-511/521 [ 66] and molecular interactions playing a role in skin physiology, formation of appendages, and skin pathology [ 54, 197, 221, 222].
The use of appropriate transgenic mouse models confirmed these findings in rodents and eventually clarified the underlying mechanism defining cyclin E1 as a promising new therapeutic target.
In addition, the molecular, genetic, and physiological tools available for the study of zebrafish and medaka provide promising avenues for defining the role of the zinc finger domain in Piccolo protein in neuronal function.
Hybrid catalysts composed of inherently insoluble compounds (defined as heterogeneous components) and inherently soluble compounds (defined as homogeneous components) are promising materials because these catalysts are expected to realize both the advantages of homogeneous and heterogeneous catalysts.
