That is unless, you don't have well defined niche.
Satellite cells, like many tissue-specific adult stem cells, reside in a quiescent state in an instructive, anatomically defined niche.
A well defined niche business will beat Wal-Mart, Costco or any other monolith in the niche they choose to operate within.
Despite the difficulties in making the recycling of plastics economically attractive on a large scale, many successful processes have been developed for more narrowly defined "niche" applications.
This confronts universities like Wits with new challenges that include, among others, the need to define niche areas of scholarship for different disciplines to work together while integrating across disciplines.
We first defined niche overlap between resident communities and the invading pathogen as the proportion of resources used by the pathogen and by at least one member of the given resident community34.
Also, profit margins in what is sometimes called the super-premium category, a fuzzily defined niche that embraces natural, organic and gourmet pet foods, can reach 40 percent, compared with 30 percent for premium brands and 20 percent for standard brands.
If Mr. Busse sounds as if he stepped out of a Frank Capra movie, it may be because he managed to turn a childhood passion for trains and the natural world into a successful career, albeit in a field — he calls it "mechanical botanicals" — that all but defines "niche".
The biofunctional network we have designed based on this knowledge may be useful as a defined niche for regulating ESC pluripotency through selective cell matrix interactions, and the method we present may be more generally useful for probing matrix interactions in stem cell self-renewal and differentiation.
Boulder, Colo.-based Pharmion focuses its attention on an even more tightly defined niche: the intersection of hematology and oncology.
