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The structure of server.R code plays an important role in defining instructions for the application, while minimizing redundant computation and maximizing application speed.
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In the guided approach using the clearly defined instructions, the inter-reader variability could be significantly reduced to a median CoV of 1.19% (range 0.84 1.89%, p = 0.001) with a considerably smaller range compared to the unguided approach (see Table 2).
Initial annotation of the wBol1-b draft genome assembly was performed using SUGAR (Simple Unfinished Genome Annotation Resource), an annotation pipeline consisting of several Perl scripts, controlled by a user defined instruction file (Szubert & Beatson, In Prep).
At its most basic, it is defined as: "Instructions promoting destructive or mean spirited behavior or activities".
The first thing that needs to be tackled prior to designing a microcontroller is to define an instruction set that the microcontroller can decode and execute and define the interface of the microcontroller.
For example, Lan et al. (2010)) defined traditional instruction as being without the support of technological devices, whereas Papadopoulos and Dagdilelis (2008) defined traditional teaching as a paper-and-pencil environment.
In addition, online-based training is defined as instruction which is delivered primarily through the internet, rather than taking place in the physical classroom in which the instructor and students are located (Benjamin et al. 2008; Means et al. 2010).
This research has implications for defining intelligence-test instructions and educational requirements in school.
Goal setting studies, in turn, may help better defining both task instructions and the way their outputs will be evaluated by the requester.
It is a story of an amazing scientific journey that started with the discovery that there exists a very special molecule in all living organisms named DNA that contains a complete set of instructions defining the organism's structures and functions.
The use of XML-based instructions defining an entire AXIOME workflow has the added benefit of contributing to these reproducible research initiatives.
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com