Sentence examples for defining for the first time from inspiring English sources

Exact(5)

In 1948, Claude Shannon published an extraordinary article, defining for the first time a mathematical model of information and determining the maximum information quantity that can be transferred over a channel, now called the shannon limit, and the limits to possible lossless data compression.

We characterized the differential effects of 6 cytokines on gene expression in a mixed population of human immune cells; defining for the first time the conserved transcriptional response to IFNω, together with IFNα and β, and revealing major similarities in IFNγ and IL12 transcriptional programs.

For patients with higher metabolite concentrations, a 26%% lower breast cancer recurrence rate was observed, defining for the first time a therapeutically beneficial threshold level of endoxifen.

In this paper, we aimed to investigate Dock10 function by defining, for the first time, the specificity of the complete Dock10 protein for "classic" Rho GTPases, and studying its effects in human HeLa cells, using stable inducible expression.

Using a combination of biochemical, genetic and imaging approaches we demonstrate that ELAV binds to discrete elements within Ubx RNAs and that its genetic removal reduces Ubx protein expression in the CNS leading to the respecification of cellular subroutines under Ubx control, thus defining for the first time a specific cellular role of ELAV within the developing CNS.

Similar(55)

Our first synthetic route defines for the first time both their relative and absolute configurations.

The guidelines are intended to define, for the first time, the kind of domestic political groups that the bureau may properly investigate.

In John Howard's "tough on drugs" era, harm minimisation was defined for the first time as the combination of supply reduction, demand reduction and harm reduction.

We measured leaflet displacements and used inverse finite-element analysis to define, for the first time, the material properties of mitral valve (MV) leaflets in vivo.

These findings define for the first time that the gastroprotective effects of KFX against gastric ulcer can be attributed to its role in NF-κB inhibition.

In order to satisfy various assessment standards, a metric called ambiguity similitude is defined for the first time to give insight on the optimizing difficulty.

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