Sentence examples for defining copy from inspiring English sources

Hence, the analysis is completed by segmenting the seqnorm-corrected profile with GLAD and, through visual assessment, defining copy number limits.

The default program settings were used in QuantiSNP for defining copy number states: EM-iters – the number of iterations used in training the model on the experimental data; L-setting – expected typical number of base pairs in a CNV-region (smoothing factor); and the maxcopy setting – maximal CN state value in the Markov model.

Many approaches including above two examples and others that are focused on defining copy number variation in the genomes are indeed capable of delineating the abundances of multiple sequences in the view of their relativity.

HACs/MACs are unique vectors with several advantages: 1) independent maintenance, 2) defined copy number and mitotically stable, 3) no silencing of the transgene, and 4) no limitation of DNA insertion size.

Control plasmids that contain approximately 1000 bases of human genomic sequence with a specific mutation of interest positioned near the middle of the insert and a nearby 6-bp molecular barcode were synthesized, linearized, quantitated, and spiked into genomic DNA derived from formalin-fixed, paraffin-embedded prepared haparaffin-embedded prepared copy number ratios.

Serial dilutions of defined copy numbers of individual qTags were included for each real-time PCR to generate standard curves, which were used to calculate the absolute copy numbers of the variable and common region in each PCR reaction mix.

A standard curve of corresponding mtDNA and nDNA template equivalents with defined copy numbers were included in each run to quantify the content of mtDNA and nDNA in each sample.

Thus, short read sequencing cannot capture unique sequence and define copy number.

We define "copy number" of a duplicon as the average number of SDs aligned to each position of the duplicon).

After finding a model with appropriate breakpoints, copy number annotations can be added to the top half of each plot to define copy number status (Fig. 1).

To define copy numbers and diversity of MIBs in macaque species, two consanguineous Mhc homozygous rhesus macaques were chosen for further analysis.