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Through these types of large-scale screens, the zebrafish model provides a means of defining connections between abnormal gene function and their respective pathways.
Zebrafish is extremely useful in terms of looking into basic mechanisms, contributions of specific genes, or defining connections between gene regulators and targets.
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And building fruitful scientific collaborations can offer an effective strategy to making career-defining connections.
The microsymbols have defined connections and weights to snapshot symbols, who are activated, if enough microsymbols are active.
"Chemists have always been in the business of taking atoms and putting them together with other atoms with precisely defined connections," he says.
The biological motivation behind is that it coarsely replicates lateral inhibition mechanisms in which neighboring similar features inhibit each other via specific, anatomically defined connections [30].
Functionally defined connections between OSN axons and mitral cells were confirmed at P5 with calcium imaging in mitral cell dendrites after olfactory nerve stimulation [44].
These genes did not have experimentally defined connections to daf-2 or its immediate connectors.
A simple input format defines the name and URL for each node, and defines connections or similarity scores between pairs of nodes.
Next, all combinations of possible non-predictive connections were added to the initial graph one at a time for a total of 25 cases, i.e. 25 = (4 regulators)* 9 response variables - 11 defined connections).
The first has to do with how you define connection.
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com