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We also discarded rs41388745 as it was mapped to both chromosome 1 and 7. Finally, by defining a threshold of 1% for global Minor Allele Frequency (MAF) of a SNP, we excluded an additional 18,875 SNPs, leaving a total of 416,644 filtered autosomal SNPs for further analyses.
Defining a threshold of functional impairment, however, remains a difficult task.
Agreement was analysed through defining a threshold of agreement based on half of the standard deviation of the HRQoL score with the highest variance.
Defining a threshold of rS < −0.5 for inverse correlation, the list of candidates was drastically reduced to 45 potential targets for NC-181, 6 for NC-1321, 29 for NC-265, and 23 for NC-350 (Table S8).
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The problem of defining a threshold for acceptance or rejection of the results is usually neglected or left to experts.
It generally involves defining a threshold to select a number of potential biomarkers based on a single measurable criterion.
It was defined a threshold of 100 ms for the rtPS average delay.
For a given hazard intensity and area covered by the hazard, we can define a threshold of impact expectation.
Others have defined a threshold of brightness temperature in the band IR10.8 to discriminate between cloud ice and cloud water (Rossow and Schiffer 1999).
The combined error from both datasets was used to define a threshold of the minimum elevation difference that could be reliably attributed to erosion or deposition in the seven years separating the sUAS and LiDAR datasets.
We then performed filtering; first, in order to avoid inter-population biases in missing data, we defined a threshold of at least three genotypes called per population sample.
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