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This is a generalization of the caching-based strategy and can be realized by defining a query as a view and caching its results (i.e., view materialization).
Defining a query takes between seconds for simple "search all compounds used as medication" type questions to tens of minutes for complex questions which traverse the full connectivity of the semantic network.
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Using this editor, the operator defines a query sample step-by-step.
It is possible to define a query based either on a single field or a combination of the following fields, i.e., PDB code, protein name, SCOP superfamily name, number of disulphide bonds, disulphide bond connectivity pattern and the number of amino acid residues in a protein chain and retrieve information that match the criterion.
We define a query gap as a set of adjacent contig positions mapped to an insertion.
Query M4 shows how to define a query that counts the number of species for each model in the graph database.
In simplest terms, the sequence of keywords that define a query might be contained in an result record, neighboring records, or both result and neighboring records.
The difference is that with archetype constraint definition, it is possible to define a query to retrieve terms from a terminology service.
The C-Map user defines a query signature associated with a particular condition of interest, which is then assessed for connection with each of the profiled compounds in the reference collection using a rank-based pattern matching algorithm.
For the ELM LIG_PCNA, for example, PDB (Berman et al., 2000) structure 1U76, which features a 15 amino acid peptide of POLD3 interacting with PCNA (Bruning and Shamoo, 2004), could be used to define a query for the PCNA interactome.
Indeed, for this SSC there is no higher class grouping in SNOMED CT, therefore we define a query as: Hemorrhage_related (is_syn some (owl:thing)) or (has_finding_site some (owl:thing)) or (has_associated_morphology some (SNMCT Hemorrhage)).
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.
Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com