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The cutoff defines the stringency of prediction: the higher the weight cutoff, the more genes are considered as being atypical.
In SSPACE the key parameter that defines the stringency of the scaffolding is 'number of links' (k), i.e. number of independent read pairs that uniquely support a connection between two contigs.
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Three user defined parameters have an impact on the stringency of co-occurrence analysis: The module size, the support, and the Z-score/P-value cutoff.
However, the stringency of the homologous match that defines a biological function is not a constant applicable to all cases.
Depending on the stringency of the predictive analysis used to define Shine-Dalgarno sequences, 269 (23%) or 551 (31%) of the genes for which we identified a primary TSS are categorized as having a 5′ UTR Shine-Dalgarno sequence.
Depending on the stringency of threshold, prevalence rates of irritability range from 3%% for severe, chronic irritability strictly defined in the Great Smoky Mountain study [ 7] to 20 % in the Isle of Wight study [ 8].
Then they showed that the stringency of environmental regulation for manufacturing firms nearly doubled between 1990 and 2008.
These inconclusive results could be due to the limited power and the stringency of our experiment.
The stringency of many CSAs may be at fault.
We combined these data with information on the stringency of national environmental policies from the World Economic Forum WEFF).
The retrobiosynthetic concept was designed to improve the stringency of isotope incorporation studies.
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