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In order to study a general and defined uptake mechanism we chose to focus on Fc-receptor mediated phagocytosis of IgG-opsonized prey, since these are present in HL-60 cells [3].
We defined uptake by the total number of drivers screened as a proportion of the total population of drivers working at the transport center.
For each network realization from Step III, we divided all uptake reactions into the following two sets: 1) a "minimal" uptake set comprising the uptakes of H2O and H+, all uptakes added in Step II, and the uptakes of the small molecules defined above (minimal set); and 2) an "extended" uptake set comprising all other defined uptake reactions in iNJ661m (extended set).
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Moreover, this investigation has been carried out to define uptake mechanism and intracellular regulation of ascorbic acid (AA) in human breast cancer cells (MDA-MB231, T47D and ZR-75-1).
In spite of its effectiveness, the use of amiloride to define uptake of cargo via macropinocytosis [23] [29] has been recently criticized since amiloride also inhibits albumin uptake in kidney epithelial cells [38] [39] and alters the cellular pH in cultured cells [40].
Further investigations to define uptake-induced phenotypes of the apoptosis inducing non-phosphorylatable survivin-mutant (T34A) have shown a caspase-dependent enhancement of chemotherapy-induced cell death, in vitro.
A score of 4 was defined as uptake higher than the liver uptake level and scattered and nonuniform F-FDG distribution and was deemed indeterminate.
A score of 5 was defined as uptake higher than the liver uptake level and centralized and uniform F-FDG distribution or as new sites of disease and was deemed positive.
In a steady state, new production, defined as uptake of preformed nitrogen (primarily nitrate) that is transported from deep waters into the euphotic zone, should equal to export production [2,3,4].
The bone emission computed tomography (ECT) showed clearly defined radiopharmaceutical uptake in the media part of the left leg.
Effect of CTB-binding on transferrin intensities in endocytic vesicles defined by uptake of GPI-linked protein.
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