The TCGA network defined four subtypes of ovarian cancer based on transcriptome, but the survival of the four types are not significantly different.
Using multi-platform omics analyses on 117 TETs, we define four subtypes of these tumors defined by genomic hallmarks and an association with survival and World Health Organization histological subtype.
Using differential patterns of intracellular expression of the N and C termini of sialophorin, we define six subtypes of breast cancer that are independent of histological and receptor status classification.
These intrinsic genes have been used to define five subtypes of breast tumors and their core expression centroids (i.e., average expression profile of the 534 intrinsic genes) in a data set of 122 breast tissue samples, most of which were locally advanced breast tumors.
We define two subtypes, namely normalized gene values of top 10 differentially expressed genes according to P-value (Feature Set Ia or TOP10) and (2) normalized gene values of all differentially expressed genes (Feature Set Ib or ALL).
If the locations harboring the specific TSGs can be defined, the two subtypes of IDC may be better characterized to have different clinical characteristics and different risks of distant relapse.
Gene expression analysis has defined five distinct subtypes of breast cancer, with predictive and prognostic implications [ 9].
After gene-expression profiling, we identified and validated gene-expression signatures that define two distinct subtypes of tumor vasculature, an understanding of which would represent an important step toward the improved design and targeting of therapeutic modalities.
We defined two kinds of lethality values.
We utilized the 'intrinsic' gene list consisting of 534 genes that have been used to define the five subtypes of breast tumors and their core expression centroids in 122 previously published breast tumors samples [ 3].
It is also unknown whether, in IBS patients with FD, psychopathological features differ between patients with the two subtypes of FD as defined by the Rome III criteria: postprandial distress syndrome (PDS) and epigastric pain syndrome (EPS) [ 2].
