Here, the stem cells are defined to be actively involved in TA cell production (instead of remaining quiescent for long periods of time); the TA population is defined to be fast dividing cells that are derived from the stem cells and that are not committed to any lineage yet.
Actions needed are: a) clarify stakeholder involvement purposes; b) define stakeholders to involve; c) motivate the previous point); d) discuss methods for achieving involvement; e) explain who should organise the process.
Social-technical approaches favor a central role of the users throughout the development process, even if defining how to involve these users is not easy [ 56].
The strategy that was defined to enable service delivery involved dividing the billing of the contract into two parts, one fixed and one variable.
The mechanisms by which mechanical forces regulate chondrocyte function are beginning to be defined and appear to involve the activation of a variety of intracellular signalling pathways, at least some of which require integrin-mediated events.
"The biggest reason is that if you want to make a great game, however you define that, is to involve your community in the making of it," he said.
It isn't defined, but it appears to involve making the Phase 1 changes permanent.
The function of Hox genes at a later phase of limb development is less well defined but is likely to involve the regulation of cell differentiation.
The upstream activator remains to be defined but is unlikely to involve Wnts since luminal cells express no obvious Wnt receptor and alveologenesis proceeds in the absence of Lrp5 [ 34].
