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One woman also felt that the question had been 'too poorly defined to answer'.
Two different populations of tiotropium users were defined to answer the study objectives Incidents users were participants receiving the first prescription of tiotropium (Handihaler or Respimat) between 1 July 2011 and 31 December 2012 (without prescriptions of tiotropium in the previous 6 months).
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An answer set of a WORL knowledge base ( KB ) of the form (langle mathcal {L},{ KB _1,ldots, KB _k}rangle ), where (mathcal {L}= langle mathcal {T},mathcal {A}rangle ), is defined to be an answer set of the WORL knowledge layer (langle mathcal {T},mathcal {A}cup mathcal {A}_1 cup cdots cup mathcal {A}_krangle ), where each (mathcal {A}_i) is an answer set of the WORL knowledge base ( KB _i).
Elsewhere, targeted surveillance was defined as surveillance "to answer a specific question about a defined disease or condition using agreed mechanisms for detection" (Anonymous, 2003), a definition which does not explicitly incorporate risk-based concepts.
Exclusion criteria: incomplete survey (defined as failure to answer questions in part 2, regarding hot aches) and duplicate surveys from the same individual determined using IP address and information from part 1.
Sample type was defined in two ways to answer the two key questions detailed above.
Acquiescence, or yessaying is defined as the tendency to answer positively to a question based on only the minimal amount of evidence, or alternately the tendency to answer too conservatively and answering positively only if the experience that is inquired has happened regularly [ 32].
Such a representation may consist of multiple hard- or soft-linked sub-models to answer clearly defined research questions.
The drop-out rate, defined as individuals who agreed to answer the overall interview but who declined to answer the section regarding headache and medication use, was 1.6%% (n = 700).
This highlights the importance of experimental design which utilizes an adequate number of samples and biological replicates to answer questions defined in the project.
Direct integration approaches are only appropriate for small numbers of highly similar datasets specifically selected to answer clearly defined questions, as opposed to recent global survey-based approaches used to identify common tissues or expression profiles across all available datasets [ 40- 42].
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