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We defined the activity of a drug as its IMDILI potential, i.e., active drugs are drugs that have known IMDILI potential and inactive drugs are drugs that are not known to cause IMDILI.
The three groups were compared by ANOVA; the "stepwise" method of the multiple linear regression analysis tested the model which best defined the activity of the masseter muscle in the sample at a significance level of 5%.
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A number of studies have defined the activities of the partially proteolyzed FVa species [ 30, 31].
It is important to define the activity of these compounds taking into account the bacterial adaptation to antibacterial agents.
However, to better define the activity of the NO-np on MRSA, a real time-killing assay was performed in tryptic soy broth (TSB) using a Bioscreen C device.
Even if the amino acids are different, it is the overall structure that defines the activity of the molecule".
It contributes to the diagnosis in defining the activity of the diseases and the resulting impairment can be quantified for compensation purposes [ 19, 21].
To define the activity of the ABCB1 and ABCG2 protein in the cell lines, the Hoechst 33342 efflux assay was determined.
First, it allowed Taunton and colleagues to define the activity of a single molecule, hypothemycin, in a whole-organism assay that, by its very nature, includes all targets.
Measurements with optimized reaction conditions, different substrates and substrate concentrations, and more sensitive analytical methods are needed to further define the activity of this enzyme.
Cell-based experiments have also been performed to help define the activity of caspase-2, yet these have yielded conflicting results.
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