Sentence examples for defined the activation of from inspiring English sources
In this study, we prospectively enrolled two independent sets of patients with gastric cancer from China and defined the activation of Notch1 by immunohistochemical staining of its active form, intracellular domain of Notch1 (ICNotch1
Using a single challenge stimulus producing consistent clinical, hematologic, physiologic and APP responses, the concentration versus time profile of this neutrophil biomarker may prove useful to define the activation of neutrophils early in the course of inflammation.
As a result, we are able to study the temporal behavior of caspase-3 activity upon stimulation of apoptosis, and explicitly define the activation efficiencies of caspases -8 and -3, which are essential for a cell's response to extracellular apoptosis stimuli.
To define the activation energy of sintering was used an analytical Eq. (1) derived by Wang and Raj: mathrm{T}cdot mathrm{c}frac{mathrm{d}uprho}{mathrm{d}mathrm{T}}=frac{1}{{mathrm{F}}^{prime}left uprho right)}cdot frac{mathrm{K}upgamma Omega mathrm{D}}{{mathrm{kTa}}^{mathrm{p}}}cdot exp left -frac{mathrm{Q}}{mathrm{RT}}right) (1).
Pathway analysis also incorporated cell cycle and TLR pathways to characterize global and comprehensive host cell response and to define the activation phenotype of macrophages in response to replicating virus.
However, most cancers are genetically complex, and are better defined by the activation of signaling pathways rather than a defined set of mutations.
This process is also defined by the activation of autophagy or ATG genes.
At the same time, subsets that are defined by the activation of transcription factors (and hence the different genetic programs) in the periphery can demonstrate plasticity [ 69].
It also provides a rationale for patient stratification defined by the activation of this pathway and the identification of target therapies.
