We sought to examine the association between narrowly defined subsets of maternal ethnicity and birth outcomes.
This analysis demonstrated that conventionally defined subsets of CD34+ CB cells are quite heterogeneous in their functional properties, transcription factor content, and signaling activities.
Genetically encoded fluorescent voltage sensors have long been desired to report voltage in defined subsets of neurons with optical readout.
This unusual form of action potential integration and persistent neural activity (barrage firing) has been observed in genetically defined subsets of interneurons of several brain areas, both in vitro and in vivo22,23,24,25,26.
Saino-Saito S, Cave JW, Akiba Y, Sasaki H, Goto K, Kobayashi K, Berlin R, Baker H. ER81 and CaMKIV identify anatomically and phenotypically defined subsets of mouse olfactory bulb interneurons.
To discuss the role of clinical trials in the changing landscape of cancer care resulting in individualized cancer treatment plans including a discussion of several innovative randomized studies designed to evaluate multiple targeted therapies in molecularly defined subsets of individuals.
The results show that despite the wide prevalence of autoantibodies, the patterns of reactivity to defined subsets of self-antigens can provide information about the state of the body.
Here, we applied the posterior probability of linkage (PPL), a method designed specifically to analyze multiple heterogeneous data sets, to the Autism Genetic Resource Exchange collection of families by analyzing six clinically defined subsets of the data and updating the PPL sequentially over the subsets.
The investigator who learns to increase the power of therapeutic trials to illuminate responses in mechanistically defined subsets of patients will not only improve clinical treatment, but also help ensure that human phenomena and concerns will steer the extraordinary engine of basic biomedical research.
Dr. Tadross' lab develops technologies to rapidly deliver drugs to genetically defined subsets of cells in the brain.
