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Patients with both aabs often have diffuse SSc and show immunogenetic features of both aab defined subsets of SSc.
As such, the ex vivo assessment of telomerase activity response to bortezomib treatment may serve as a prognostic feature and add to the therapeutic armamentarium by the addition of telomerase inhibitors in defined subsets of patients.
Turtle, C. et al. Immunotherapy with CD19-specific chimeric antigen receptor (CAR -modified T CAR -modifiedned subseT cellssitiof.
Since selection of the optimal combination of candidate features is a combinatorial problem, we first reduce the size of the search space by defining a predetermined subset of features used in all feature-selection iterations.
The most commonly used method for partitioning alignments, and the only one currently suited to very large datasets, is to define subsets according to structural features of the sequences in the alignment, such as gene boundaries, codon positions, structural components of rRNAs (such as stems and loops), or some combination of these.
Selecting the best subset of features in a large hypothesis space defined by all possible combinations of features is a well-known issue in machine learning.
Its goal can be summarized as follows: in the search space defined by all possible subsets of features in conjunction with a variable number of clusters, it assigns a ranking score to each partition that may be defined.
Different feature selection algorithms were tested to select the optimal subset of features.
Finally, support vector machines (SVMs) are trained using the selected subset of features.
We used the subset of features suggested in [15].
For each subset of features, the method computes classification accuracy.
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