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CsrA has a clearly defined specificity based on binding to a specific mRNA sequence to inhibit translation.
The variants have a defined specificity, as they could be shown to specifically target galactose-decorated xyloglucan structures (such as XLLG).
T lymphocytes can be redirected to recognize a tumor target and harnessed to combat cancer by genetic introduction of T-cell receptors of a defined specificity.
The multi-epitope contraceptive vaccines and preformed engineered antibodies of defined specificity may eliminate concern related to inter-individual variability of the immune response.
In this method, a sVD of a defined specificity is genetically fused to either the N-terminus of the light chain or the C-terminus of the heavy chain of a functional IgG antibody of a different specificity.
Recombinant DNA technology enables the manufacture of proteins and antibodies with a defined specificity and uniformity, which is a vast improvement over previous methods of production by extraction and purification from human or animal blood and tissues.
Similar(41)
Taken together, our findings demonstrate that the PIN molecule is a suitable scaffold to expose new peptide loops and generate small artificial ligand-binding products with defined specificities.
Significant efforts and progress have been made to engineer DNA binding domains with defined specificities.
These public or near-public TCRs provide template libraries for α and β chains with defined specificities.
They consist in complex arrays of binding sites with defined specificities but susceptible of rearrangements without loss of function.
The more frequent public combinations turn out to be, the more narrowly defined specificities can be and remain detectable, and vice versa.
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CEO of Professional Science Editing for Scientists @ prosciediting.com