Sentence examples for defined site from inspiring English sources

A key issue for structure-based drug design is if there are distinct outcomes from a single structurally defined site.

Once brought into position on the gene of interest, Cas9 acts like a molecular pair of scissors, cutting the target sequence at a defined site.

We are constructing a plasmid vector that will allow insertion of any gene of interest at a defined site on the Bacillus anthracis chromosome.

Each step has been studied in vitro using cell extracts or highly purified repair factors and radiolabeled DNA of known sequence with DNA damage at a defined site.

A region that bound mouse Abs overlapped with a recently defined site on BoNT/B that binds to mouse and rat synaptotagmin II, thus providing a molecular explanation for the blocking (protecting) activity of these Abs.

The multi-copy insertion of transcriptional reporter constructs into single genomic sites in mammalian cells provides the signal intensity needed to investigate transcriptional dynamics at a defined site.

EPL therefore allows us to engineer proteins with chemically defined, site-specific modifications.

Using this approach, the site composition of five defined sites with increasing size up to 8 nm was obtained.

This complete change in the UAG meaning enabled protein synthesis with these non-natural molecules at multiple defined sites, in addition to the 20 canonical amino acids.

Progress has been made, but the quantitative delivery of a nanocarrier to defined sites in tumors is neither inevitable nor yet predictable.

Consequently, the ability to engineer redox active centers at defined sites in proteins would facilitate both the study and manipulation of a wide range of biological processes.