Sentence examples similar to defined mutation rates from inspiring English sources

Following Lambert et al. (2002) and Millar et al. (2008), we define mutation rate as the rate at which a base substitution is incorporated into all mitochondrial genomes of an individual.

We defined the mutation rate as "the percentage of mutant genome copies per sample".

We defined the mutation rate to be 1.5 × 10−8 and simulated 5000 haplotypes with 500 000 base pairs.

As in figure 2, this prediction is well supported by simulations of a replication fidelity locus with an array of alleles differing in the mutation rate by a constant factor (and acting in an additive fashion to define the genotypic mutation rates), with deleterious mutations assumed to arise in a freely segregating background.

Here we study how a system can cope with externally defined requirements under various mutation rates (per base).

Every time that a sequence replicates, each of its nucleotides has a probability (defined by the mutation rate μ) to be replaced by another nucleotide, randomly chosen among the four possibilities.

This process is defined by the mutation rate μ and by the characteristic function M x) = Σ r > 0 m r cos (rx).

Mutation rates define the plausible time frame of acquisition events in bacteria and are critical now that genomic data are increasingly being relied upon to refine transmission epidemiology.

We define an overall mutation rate per gene and specify the relative ratio at which point mutations, duplications, deletions, and rearrangements take place.

The overall mutation rate μ is defined as the sum of mutation rates over all divisions in the development.

Briefly, we calculated the number of expected de novo mutations across the three genes by summing the gene-specific mutation rates [as defined by Samocha et al. (12)] by the number of transmissions (i.e. twice the number of probands).