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A clinical PET study [11C]GSK189254 indicated that V T values for this radioligand were markedly reduced in all ROIs including the cerebellum and pons by treatment with an H3R ligand, AZD5213, and it is accordingly likely that no reference region can be defined in the human brain [14].
Over 50 AKAPs have been defined in the human genome.
Multiple pseudogenes for the F0 motor proteins have been defined in the human genome.
Muscularis mucosa is not very well defined in the human bladder and sometimes seems to be absent [ 1].
Over 510 kinases including 85 tyrosine kinases have been defined in the human genome, while only ∼150 phosphatases including 81 tyrosine phosphatases are known.
This suggests that either there are a substantial number of imprinted regions yet to be defined in the human genome or that ASHM is often located distinct from imprinted loci.
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As for SNPs, we can use this functional annotation of the human genome in RVASs by grouping variants not only by genes but also on the basis of regulatory sequence coordinates defined in the appropriate human cell type or tissue.
The mechanism(s) underlying the observed association between VDT and decreased tear secretion are not defined in the present human study [10], [11].
For each gene in both gene sets, the number of human-specific TF-binding sites with genomic coordinates showing relative proximity to protein-coding gene boundaries defined in the hg19 reference human genome database was calculated.
Similar to the analyses performed for protein-coding genes, the number of human-specific TF-binding sites with genomic coordinates within a relative proximity to lncRNA gene boundaries defined in the hg19 reference human genome database was calculated for each lncRNA.
The right to life is, after all, the first right defined in the European convention on human rights.
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