Sentence examples for defined in a twofold from inspiring English sources

Harmful interference is defined in a twofold way.

Renal dysfunction was defined as a twofold increase in baseline serum creatinine level or an increase in serum creatinine level of 176.8 μmol/L (2.0 mg/dL), leukopenia (<4 000 leukocytes/mm) and leukocytosis (>11 000 leukocytes/mm).

Firstly, the proportion of patients who developed L-AmB related nephrotoxicity defined as a twofold increase in serum creatinine compared to baseline was similar in the randomized controlled trial which gave rise to the number needed to harm of L-AmB vs caspofungin and the LEAD study [ 7, 8].

A positive response (defined as a twofold increase in antibody titer from baseline) to tetanus vaccination at 28 days was seen, however, in ≥ 60% of subjects across all treatment groups versus 75% of control subjects.

In their observational study of 1,013 patients with shock, hyperoncotic albumin was associated with a fivefold increased risk of renal event, defined as a twofold increase in creatinine or need for dialysis [ 10].

They found that the HES group had a significantly higher incidence of ARF (defined as a twofold increase in creatinine, 42% versus 23%; P = 0.028), and in a multivariate analysis, the use of HES was associated with an odds ratio of 2.57 for ARF.

Acute kidney injury (AKI) was determined using risk, injury, failure, loss, end stage (RIFLE) criteria, defined as a twofold increase in serum creatinine, or an estimated glomerular filtration rate (eGFR) (according to the Modification of Diet in Renal Disease (MDRD) study equation) decrease by 50percentt compared to baseline [ 16].

Differential expression was defined as a twofold or greater difference in expression.

The flux along the matrix series in the domain of natural numbers is defined as a twofold series, but with the summing order changed.

A positive response to PPV23 was defined as a twofold or >1 mg/L increase from baseline at week 8. Secondary end points, safety assessments, analysis populations and antibody measurement methods are described in online supplementary text.

Acute kidney injury was defined as a twofold increase of serum creatinine levels during the observation period, as this was consistently reported in the four trials with data on kidney function.