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On the whole, the inherently exploratory nature of the investigation framework introduced by this paper differs from the standard experimental procedures that rely on an a priori defined hypothesis to design a paradigm that addresses a specific cognitive process.
The alternative hypothesis for branchXsites tests of Yang, Nielson and colleagues (implemented in codeml) have fewer parameters than the unconstrained switching model implemented in fitmodel, and thus this approach may have more statistical power when one has well defined hypothesis for the branch on which switching is expected to have occurred.
However, targeted experiments involve the absolute quantification of a small number of metabolites (around 20 or less) to test a defined hypothesis.
Based on the already known data and ideas, conditions of progene formation can only be described as an approximate scenario rather than a clearly defined hypothesis.
Although both studies aimed at tapping different levels in the mental lexicon, the present paper explicitly investigated selection effects based on a neuroanatomically defined hypothesis.
The latter case would mean that more narrowly defined hypotheses reflecting the set of conditions imposed by each experiment could be true even if the original, more broadly defined, hypothesis described above were not true.
Similar(51)
Expression profiling using microarrays is generally considered "discovery research," although it can also be a powerful approach to test defined hypotheses.
Based on the combination of our reviewed sources and data outside the field of sleep studies, or from other geographical locations, we defined hypotheses to be confirmed or infirmed, which allowed to summarize a research agenda.
We defined the construct validity as being good if > 75% of our own defined hypotheses could be confirmed.
Instead, the EPR is intended to answer refined phenotyping questions, with narrowly defined hypotheses and specific, measurable end points.
We did not adjust for multiple testing since this study focused on a few a priori defined hypotheses.
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