In this scenario, the first-born red cones instruct the adjacent undifferentiated progenitors via cell-cell signaling to assume defined fates.
Others involved the two veteran quarterbacks — Drew Brees of the Saints and Kurt Warner of the Cardinals — in moments that defined the fate of their teams.
Her books include Voices of Chernobyl, a collection of oral interviews with survivors of the 1986 nuclear disaster that defined the fate of the former Soviet Union.
Sox9 expression in digit condensations lies within domains of digit progenitors defined by fate mapping; digit 3 condensations express Hoxd13 and Sall1, digit 4 condensations Hoxd13, Tbx3 and to a lesser extent Tbx2.
However, the pathways/mechanisms that determine defined cell fate remain to be elucidated.
Consequently, a single defined cell fate map applicable to all individuals cannot exist.
In most cases, cells that had at least acquired a defined cell fate were detected in ectopic locations reflecting the lack of retinal lamination.
We therefore defined cell fate as a binary gene expression profile where each gene is either ON or OFF; this is a course-grained definition that captures combinations of genes expressed in each cell.
That conclusion ricocheted through the culture as a defining fate for women of that age, but 20 years later the magazine issued a retraction, in an article entitled "Rethinking the Marriage Crunch".
