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Proposed definitions are ambiguous, and extensive drug resistance is encompassed by the already defined extensively drug-resistant (XDR) TB.
Identity has also been defined extensively in the nursing literature.
We defined extensively drug-resistant TB (XDR-TB) as MDR-TB with further resistance to ≥3 of the 6 classes of second-line drugs.
Thus, we defined extensively drug-resistant TB (XDR-TB) isolates as those meeting the criteria established for MDR-TB plus resistance to ≥3 of the 6 classes of second-line drugs.
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XDR-TB is a term sometimes used to define extensively resistant TB, and constitutes one in ten cases of MDR-TB.
The Thursday session was devoted to the emerging global challenge posed by multidrug-resistant tuberculosis, known as MDR, the most lethal form of which is defined as extensively drug-resistant tuberculosis, known as XDR.
One strain was defined as extensively drug resistant (XDR), in this case resistant to amikacin and ofloxacin.
Isolates nonsusceptible to all tested aminoglycosides, fluoroquinolones, β-lactam, β-lactam/β-lactam inhibitors, and carbapenems were defined as extensively drug-resistant (XDR).
However, this assumption is markedly discrepant with evolutionary theory, whereby fitness is a dynamic property of phenotype and is defined and extensively modified by environment [ 14, 15].
"Hyperkeratosis" (yes/no) was defined as extensively thickened keratosis observed on the palm or dorsum of the hands and/or the sole or plantar of the foot that are easily visible from a distance.
Isolates nonsusceptible to all the tested aminoglycosides, fluoroquinolones, β-lactam, β-lactam/β-lactam inhibitors, and carbapenems were defined as extensively drug-resistant (XDR) [ 20, 21].This is a modification of the ECDC definition for XDR, which is defined as non-susceptibility to at least one agent in all but two or fewer antimicrobial categories [ 20].
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