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We then combined epigenetic modification of HFFs with hESC extract treatments and more defined evidence of reprogramming was observed.
We defined evidence as peer reviewed publications in which the clinical effectiveness of a particular device was assessed.
Furthermore, such an approach would have lacked the flexibility to review a broad, rather diffuse and poorly defined evidence base which was possible with our more comprehensive approach.
Bowen Zwi et al. also defined evidence broadly to encompass research, opinion and views of individuals or groups, results of consultative processes and published reports and documents [ 13].
Regulators appear to be willing to accept such approaches where use is clearly defined, evidence is strong, and approaches are qualified for regulatory use.
Although the function of smHSPs has not been defined, evidence suggests that they serve as molecular chaperones to protect cells from stress damage, but that they are not required for normal cellular function [ 23].
Similar(49)
Purpose: This prospective study is designed to disseminate and apply 5 previously defined, evidence-based guidelines in children with isolated spleen or liver injuries.
The IPC position stand, published in 2009, defined evidence-based classification and provided guidelines on how an evidence-based classification system may be achieved [2].
Our current implementation of SeeBot has the average evidence degree 23 among all defined evidences.
By contrast, GSURV is large, comprehensive, and provides contemporary locally defined evidence-based data that takes into account the contribution of a much broader range of foods.
Proportion of patients assessed for ART eligibility, proportion of eligible patients who were started on ART and proportion receiving defined evidence-based interventions (including prophylactic co-trimoxazole and tuberculosis screening).
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com