Sentence examples for defined based on prior from inspiring English sources

Therefore, we analyzed the microarray data using Gene Set Enrichment Analysis (GSEA) [ 33] to identify gene sets defined based on prior biological knowledge, such as the Gene Ontology category.

Gene Set Enrichment Analysis (GSEA) [ 29], was used to find whether a set of genes defined based on prior biological knowledge (e.g., those in a common signaling pathway) shows statistically significant correlations with IL6.

This strategy is very similar to what has been performed for analysis of multiple genes using gene arrays: although it is possible to set up arrays using very large numbers of gene, it is also possible to use gene sets containing smaller numbers of genes that are defined based on prior biological knowledge, for example, published information about biochemical pathways [ 44].

The relevant areas for the combined SPECT/CT examination were defined based on a prior whole-body planar scintigraphy.

Polymorphisms were examined individually and in genotype groups defined based on our prior work [ 6].

An outlier can be defined based on specifying the prior probability of not having any outliers as very high, say 95%.

Note that all the ROIs were defined based on the t-maps prior to cluster-size correction (P < 0.001).

Covariates were selected based on the previous literature (Woolf and Åkesson 2003; Lee et al. 2015; By the American Geriatrics Society 2015 Beers Criteria Update Expert Panel 2015; Zia et al. 2015; Nurminen et al. 2013) and were defined based on claims during the 12 months prior to initiation (Additional file 1: Table S3).

Priors are defined based on what is known from the species biology, or based on estimates for similar species.

Work status and living status were defined based on the patients' status during the 4 weeks prior to baseline.

Positive hs-CRP was defined based on local laboratory levels (>1.0 mg/l or >3.0 mg/l), and population-based and prior study values >2.0 mg/l.