The MIC is defined as the lowest concentration of a formulation that visibly inhibits in vitro microorganism growth.
For easier formulation, is defined as the (fictitious) highest possible ask and is the lowest possible bid.
The CSCCP can be defined as the following floating point linear programming formulation: mathop {hbox{max} }limits_{top R} mathop prod limits_{i = 1}^{n} p_{{i,x_{i} }} (1) mathop sum limits_{i = 1}^{n} m_{{i,x_{i} }} = W_{0} (2) x_{i} in left{ {1,2, ldots,K_{i} } right},forall i in left{ {1,2, ldots,n} right}.
The TOA/TAC ratio was defined as the oxidative stress index (OSI); its formulation is as follows: OSI (arbitrary units) = [TOA/TAC] × 100 [ 25].
The entrapment efficiency (EE) of the GEM within developed formulations was defined as the drug content and was calculated by employing (1) as follows: (1) % Entrapment Efficiency (EE ) = X 1 − X 2 X 1 × 100, where X1 = amount of total GEM taken (mg) and X2 = amount of free GEM detected after ultracentrifugation (mg).
"Chlorhexidine" was defined as the application of any concentration of chlorhexidine in any formulation to the oropharynx.
Bioavailability is defined as the rate and extent to which the active ingredient in a drug formulation becomes available at the site of necessary action [3].
This case is defined as the clustered generalized vehicle routing problem and both of the proposed formulations of GVRP are adapted to clustered case.
Relative exposure, defined as the ratio of AUC0- t ' of U-500R versus U-100R formulations, was assessed using a linear mixed-effects model, which included treatment, period, and sequence as fixed effects and the subject as a random effect.
The advantages in cancer cell inhibition of the CA-PLA-TPGS nanoparticle formulation > PLA-TPGS nanoparticle formulation > commercial Taxol® formulation could be quantitatively demonstrated in terms of their IC50 values, which is defined as the drug inhibitory concentration that is required to cause 50% tumor cell mortality in a designated period.
