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The alignment coverage was defined as the alignment length divided by the length of the shorter sequence.
The conserved microsyntenies were defined as the alignment regions where carp BAC clones had ends ≤ 300 kb apart on the same chromosome and with the same orientation.
A tile is defined as the alignment of one group of ordered residues on the subject sequence with a partition of ordered residues on the query sequence.
Following the work by Culham et al. [ 26] neutral position with respect to shoulder protraction was defined as the alignment of the clavicle of 20° inclination in the transverse plane with respect to the medio-lateral axis of the thorax.
If the related to these locations are augmented in a single string, the Primary Pole Score for that particulate PP is defined as the alignment score of that augmented string (with respect to the scoring matrix used for the whole alignment).
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To be consistent with the key hypothesis that acetylation is based on the structure reorganization of the lysine's flanking peptide, raw distance is defined as the local alignment score with BLOSUM 62 matrix and Smith-Waterman algorithm[ 11], and length normalized distance is equal to raw distance divided by the minimized length of the pair-wise alignment peptides.
In Prefab, the reference alignment is defined as the portions of alignments consistently aligned by two structural aligners: CE (Shindyalov and Bourne, 1998) and DALI (Holm and Sander, 1995).
We defined a match as a BLAST hit of ≥ 99% identity and ≥ 0.8 alignment coverage, which we defined as the ratio of alignment length to the BES length.
All subtrees with at least three leafs are then ranked by their quality, which is defined as the average pairwise alignment scores of its leafs.
The optimal 'left' and 'right' breakpoint of the structural variant in the read is then defined as the maximum total alignment score using the two scoring vectors f and r.
Those pairs that satisfy a divergence threshold (defined as the fraction of the alignment total length) are used for the calculation of evolutionary distances.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com