In many cases, a fracture propagation can create a branch pattern and a complex fracture networks around the hydraulic fractures (Ali Daneshy 2003), which were defined as stimulated reservoir volume (SRV) (Mayerhofer et al. 2010; Wang et al. 2014).
The final read outs are expressed as induction index (arbitrary units) defined as stimulated subtracted by reference condition, i.e. only media culture.
Relative adrenal insufficiency was defined as stimulated cortisol less than 18 μg/dl.
Yet, even those with "minimal" RBF, defined as stimulated C-peptide level of 0.04 0.2 nmol/L, showed lower incidence of severe hypoglycemia compared with the group with undetectable RBF (7).
Post hoc analysis of DCCT data demonstrated that those with preserved C-peptide, defined as stimulated C-peptide, value >0.6 ng/ml, had superior clinical outcomes, including less hypoglycemia and retinopathy, than those with lower C-peptide (13).
Bioactive materials are defined as materials stimulating a specific biological response at the interface between the material and tissue, resulting in the formation of a bond between them [ 24].
Outcome measures included peak stimulated C-peptide concentration during the MMTT, incremental C-peptide area under the curve (AUC), and clinically important C-peptide response, defined as peak stimulated C-peptide concentration >0.2 nmol/L (26).
The hemisphere evoking the largest pharyngeal MEPs was then defined as the stimulated hemisphere.
A positive response to hypoglycemia was defined as a stimulated value greater than 3 SDs from the respective baseline during euglycemia.
GHD was defined as a stimulated GH level <10 μg/L after clonidine/arginine, <4.1 μg/L after GHRH-arginine, and <0.4 μg/L after arginine.
