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On the other hand, we also reported the list of genes with expression level lower than the given thresholds only in a specific condition (defined as specifically not expressed).
We also analyzed the number of genes that showed the expression level higher than specified thresholds (0.3 and 1 RPKM, respectively) only in one condition (defined as specifically expressed).
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A bioreactor is defined as a specifically designed vessel to facilitate the growth of organisms and cells through application of physical and/or electrical stimulus.
It should also be noted that both Brazil and East Africa are reported destinations for UK 'sex tourism' (defined as travel specifically for the purpose of engaging in sexual activity) [35].
MTAs were defined as agents specifically modulating pathways different from those triggered by cytotoxic agents, including DNA, tubulin or the cell division machinery (Le Tourneau et al, 2011).
For our analysis, genes with a positive PEM score achieving FDR < 0.25 were defined as tissue-specifically over-expressed whereas genes with negative PEM score and a FDR < 0.25 were defined as under-expressed.
Only studies in which physical symptoms were operationally defined as MUPS or specifically referred to as functional, somatic, or non-specific were included.
Farm equipment was defined as vehicles designed specifically for agricultural operation (2014) such as combines, farm tractors, fertilizers, feeders, towed grain carts, and wagons.
DAMPs have been defined as endogenous molecules specifically generated upon tissue damage.
An ongoing clinical trial for lung cancer was defined as a trial specifically focusing on lung cancer and not including other solid tumors or malignancies that had been approved by the Institutional Review Board IRB / Independent Ethics Committee (IEC) and was open for recruiting subjects.
Effectively, this strategy constructs the field to be known as having specific boundaries, defined as research that has specifically addressed the review question, used particular study designs and fulfilled the procedural requirements for the proper execution of these.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com