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Progression was defined as progressive excavation of the optic disc (funduscopic and controlled by the Heidelberg retina tomography – HRT) and/or progressive visual field loss in the Humphrey perimeter over the last 6 12 months.
The progression of diabetic nephropathy was defined as progressive albuminuria, end-stage renal disease, or induction of hemodialysis.
TP53 mutastions were associated with chemoresistance, defined as progressive disease on therapy (p = 0.0358; p = 0.0136 for mutations affecting p53 loop domains L2/L3).
Treatment failure was defined as progressive disease despite therapy.
Platinum refractoriness was defined as progressive disease/stable disease on primary platinum chemotherapy.
Clinical evidence of new lesions or growth of the tumor was defined as progressive disease (PD).
Similar(38)
Local progression is defined as a progressive disease (PD) according to RECIST.
Overdiagnosis was defined as non progressive tumours diagnosed as cancer at histology or progressive cancer that would remain asymptomatic until time of death for another cause.
Treatment response (TR) was defined as non-progressive (non-PD) and progressive disease (PD), by morphologic RECIST or clinical criteria at q4 and q10.
This is defined as a progressive disease and death in consequence of that disease can reasonably be expected within six months.
Physiological shock may be defined as acute progressive circulatory failure, in which the tissues receive an inadequate supply of blood and its components (such as nutrients and oxygen) and an inadequate removal of wastes.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com