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Those converted values are defined as principal components.
ActivityScore for each gene is calculated based on the observed effect (R) of its neighbors; genes that have high ActivityScore are defined as principal regulators.
As the focus of this study was community-acquired pneumonia (CAP), we excluded from the cost analysis any health-care associated or hospital-acquired pneumonia, which was defined as principal diagnosis on an inpatient claim that had evidence of an acute-inpatient or long-term care stay in the previous 30 days.
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The dataset also included the principal diagnosis, defined as the principal condition causing the patient's admission to the hospital, and up to 19 additional diagnoses.
These synthetic variables are defined as the principal components.
The circadian system is defined as a principal pacemaker in the suprachiasmatic nucleus (SNC) in coordination with a number of peripheral circadian oscillators.
For the purpose of this study, technology entrepreneur is defined as a principal actor in the founding of at least one technology-driven or technology-based business venture, whether or not the venture(s) persisted as going concern(s). 2.
Glaucoma was defined as the principal cause of visual impairment if the optic cup-to-disc ratio was greater than 0.6, in the absence of another cause of reduced vision.
It is defined as the principal eigenvector of the adjacency matrix of the network.
A cluster has been defined as a principal village and its associated LHWs.
In the case of coexisting collateral connections, the prominent one was defined as the principal.
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com