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Premature menopause is defined as onset before 40, while early onset menopause occurs before 45.
Boston Children's Hospital (BCH) has amassed a cohort of children with very early onset psychosis (VEOP, defined as onset before age 13).
Two subsequent reports showed that the linkage evidence increased in the subset of families with phrase speech delay (PSD), defined as onset of phrase speech later than 3 years of age.
Early menarche was defined as onset of menstruation occurring between ages 8 and 11 years.
NDM was defined as onset of diabetes mellitus diagnosed before 6 months of age.
Type 1 diabetes was defined as onset before age 40 years and permanent insulin initiated within 1 year of diagnosis.
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dEarly diabetes onset was defined as a onset before 7 years of age.
Acute onset was defined as symptom onset ≤3 days before presentation.
Disease onset was defined as the onset of the first non-Raynaud's symptom.
Eighteen patients (60 %) had late-age onset AAV, defined as disease onset at age 60 years or greater.
Cases were defined as early onset if age of onset was <65 years with AD and as late onset if age of onset was >65 years.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com