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Mild acute GvHD was defined as grades I II, and severe, as III IV.
Status of liver function was defined as grades A, B or C based on the Child-Pugh classification [ 20] and Model for End-stage Liver Disease (MELD) Score was calculated [ 24].
Exclusion criteria were confounding neurological and psychiatric disorders, systemic opportunistic infection, severe hepatotoxicity (defined as grades 3 or 4 by AIDS Clinical Trials Group [ 48]), and moderate/severe renal insufficiency [ 49].
In the present trial, we are able to demonstrate a pCR in 23% of patients, defined as grades 3 and 4 according to the Dworak classification (Dworak et al, 1997) following preoperative therapy with a single cycle of XELOX and two further cycles of CAPOX given with radiotherapy.
Similar(56)
The presence of WMLs was defined as Grade 2 or greater in this study.
Mast is defined as Grade A equipment which is essential for the safety and continued combat capability of the ship.
Dose-limiting toxicities (DLTs) were defined as grade 3 4 leukopenia, thrombocytopenia, anemia, fever with grade 4 neutropenia and more than grade 2 non-hematologic toxicity, with the exception of nausea, vomiting, and alopecia.
Notably the independent prognostic value of the profile held true regardless of whether low grade was defined as grade 1 or grade 1 and 2 disease (Table 3).
Temperature was measured with an oral thermometer; fever intensity was defined as grade 1 37.5°CC to 38°C), grade 2 >38°CC to 39°C) or grade 3 >39°CC).
Histological grade was defined as Grade I, Grade II, or Grade III.
dLow and high grades are defined as grade 1 2 and grade 3, respectively.
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CEO of Professional Science Editing for Scientists @ prosciediting.com