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Thus, in order to create and cover a spherical particle, HEF must form a precisely defined arrangement of pentagons and hexagons.
Within the last decade a host of chemical approaches has been developed with the goal to produce synthetic chromatin with a defined arrangement of PTMs.
In a rational protein design study a metal-binding site was functionally grafted on the solvent-exposed surface of the β-barrel, whereby the rigid backbone conformation permitted the spatially defined arrangement of three His side chains.
A defined arrangement of motifs among many post-synaptic proteins is a well-recognized architectural feature of the complex.
Upon UV irradiation, the APB moiety decomposes to yield a nitrene that covalently inserts itself at two specific DNA sites, hence suggesting a defined arrangement for the H2A N-terminal tail with respect to nucleosomal DNA.
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In the design of multicompositional materials with spatially defined arrangements of the different components, block copolypeptides may be highly useful as structure-directing agents for nanoparticle assembly [10].
The intricate network of billions of these neural cells, presumably organized in defined arrangements to impart specific neural activity, gives rise to thoughts, feelings, memories and life as we know it.
As these techniques improve in areas such as spatial resolution and speed of patterning, they will continue to grow in value as model systems for understanding cell responses to spatially regulated bioactive factor signal presentation in vitro, and as strategies to investigate the capacity of the defined spatial arrangement of these signals to drive bone regeneration in vivo.
We suggest that the SSU head component rpS5, together with platform components as rpS14, is a crucial constituent of a highly defined spatial arrangement in the head – platform interface of nascent SSUs.
The apparent binding constant Kd' calculated in our study is used primarily to compare the relative binding affinities of different recombinant HAs by taking into account a defined spatial arrangement of HA (that is fixed for all the HAs) relative to the glycans.
We suggest that the SSU head component rpS5 and platform components as rpS14 are crucial constituents of a highly defined spatial arrangement in the head – platform interface of nascent SSUs, which is required for efficient processing of the therein predicted SSU rRNA 3' end.
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