Sentence examples for defined activate from inspiring English sources
Therefore, we can speculate that L.m-induced inflammatory stimuli such as IL-12 and/or IL-18 (and others that remain to be defined) activate the bystander secretion of IFN-γ observed in memory CD8+ T cells [43], [44].
Finally, a defined activated function performs a mathematical operation on inputs and results the outputs.
These results also emphasize that α-SMA, the most commonly used CAF / myofibroblast marker, should not be used solely to define activated fibroblasts.
Because at 2 days post-activation, TN cells still remain CD45RO negative, we used GARP and CD45RO as markers to define activated Tregs following 2 day TCR stimulation of total CD4+ cells (Fig. 2A).
The majority of these have included PTEN loss or PIK3CA mutations to define activated PI3K pathway.
In order to define activated genes within the detected subtle copy number increase, we performed an in silico analysis of vast amount of existing gene expression data [ 22], including a considerable collection of normal peripheral nervous system and neuroblastoma samples.
Our study defines activated microglia as the prominent IFNβ-producing cell type in the CNS as characterized by an intermediate CD45 and high Iba1 expression as well as a hypermorphic-rounded morphology in the IFNβ/YFP fluorescence reporter mouse model [ 42- 44].
For example, with two genes with a known activating relationship from STRING (JUN and ATF3) [ 52, 53], bins defined as activating have non-zero values while bins defined as inhibitory have mostly zero values.
This is a matter of debate since these calcium channels are classically defined as activated by high cell membrane depolarization in excitable cells.
FACs analysis showed that FLNa-deficient human melanoma M2 cells express α5β1 integrin, but not αvβ3 (Fig. 4A), both of which are high affinity (defined as activated) integrins [33], [34].
Nine of the initial ten networks were randomly generated, i.e. for the defined nodes activating, inhibiting or no edges were sampled.
