Sentence examples for define the responsible from inspiring English sources

If B cells are conclusively shown to participate in the development of transplantation tolerance, it will be important to define the responsible mechanisms in order to design monitoring assays and immunosuppressive regimens that favor the development of tolerance.

Looking at a surgical process it is obvious to define the responsible surgeon as the process owner and the "customer" of information.

Taken together, the IBD mapping and recombination breakpoint defined the responsible locus within an interval of ∼2.0 Mb delimited by markers ss71867771 and ss131045198 (Fig. 3B).

The present studies were designed to identify the immune responses induced by ICP10ΔPK and define the component responsible for protective activity.

When it comes to how to run our great country, I guess it depends on how you define the word "responsible".

To define the mechanisms responsible for stabilization of dimer assembly in native AMPA receptors, contacts between the adjacent ligand binding cores were individually targeted by amino acid substitutions, using the GluR2 crystal structure as a guide to design mutants.

To address in-reactor failures, efforts are underway to define the mechanisms responsible for in-reactor pillowing, and to suggest improvements to the fuel plate design and operational conditions.

To further define the domain responsible for Bves-Bves intracellular interaction, a solid phase SPOTs methodology was employed.

Further work is needed to define the mechanisms responsible for the antiproliferative effects of pharmacological inhibitors of BK and IK1, such as paxilline, penitrem A, clotrimazole, and TRAM-34.

To further define the region responsible for dauer expression, smaller deletions were made from the region deleted in pWBI066, using the same PCR strategy, to make pWBI074 (59-bp deletion), pWBI075 (109-bp deletion), pWBI076 (159-bp deletion) and pWBI077 (209-bp deletion).

We analyzed multiple rad2 C-terminal deletion (rad2CΔ) mutants to define the sequences responsible for the CS-like phenotypes and examine the roles of those sequences in various cellular mechanisms.