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Clearly, further studies in polymicrobial sepsis of rodents are necessary to define the interactions of the IL-17/IL-23 IL-17/IL-23 IL-17/IL-23
More detailed experiments aimed at understanding the mechanistic interplay of PUF60 and U2AF65 are required to better define the interactions of these proteins and the precise role of PUF60 in 3' splice site selection.
combine native mass spectrometry and chemical crosslinking to define the interactions of the Hsp70/90 chaperone system.
First, they could contribute to define the interactions of these cells with the microenvironment and help explain how the mechanisms of senescent cell clearance work.
Because IL-13 also binds to IL-13Rα2, we used coIP, signaling, and Biacore experiments to define the interactions of IL-13, Chi3l1/YKL-40/BRP-39, and IL-13Rα2.
To further define the interactions of irradiation and β1-, β3-integrin and MMP-2, ECM-mediated cell survival and β1- and β3-integrin-dependent cell adhesion and invasion was examined in four human glioma cell lines with different invasive and tumourigenic potentials.
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In the present study, we extended these findings by using a 4×3 factorial design (n=5/group) to define the interaction of a range of doses of amylin (0, 4, 20, 100 μg/kg/d) and PYY(3 36) (0, 200, 400 μg/kg/d) on FI and BW loss following 2-week subcutaneous (SC) infusion in DIO rats.
Investigations into the mechanisms underlying the effects of ALA-PDT+HT are to be carried out to more clearly define the interaction of the therapy components.
Although, additional investigations are required to better define the interaction of competing peptides in the parasite, the proof-of-concept finding of derived peptides from regulators of PfPP1 that inhibit the binding of PfI2 to PfPP1 and, in consequence, parasite growth is an important advance.
We have previously structurally defined the interactions of Rab8A with its GEF Rabin8 (Guo et al, 2013).
As a general consideration, the development of comprehensive models is difficult and has to contend with the integrated network nature of the system, where the addition of one novel component necessarily requires defining the interactions of the new item with the remainder of the network.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com