Sentence examples for define stringent from inspiring English sources

Additional studies designed to assess the amount of neutralizing antibody to AdHu5 in the lung over time after intranasal administration of varying doses of AdHu5 are currently underway in an effort to further define stringent conditions under which pre-existing immunity can be established for experimental testing.

Computational TFBS prediction methods are often marred by high false positive rates (FPRs), so we initially sought to define stringent filters for the algorithm in order to focus on highly-likely TFBS motifs.

It was important to do this exercise for two reasons: firstly to improve the diagnosis of an uncommon condition and improve patient care, and secondly to define stringent diagnostic criteria so that robust clinical trials can be carried out to improve current patient management.

By manually comparing these critical genes and also some of the reciprocal hits with the data form Jackson et al. [ 11] and inspecting them visually on the genome browser for synteny, we were able to define stringent orthologous and species-specific genes.

Firstly, we defined stringent cutoffs for the qPCR data in order to compile a list of true positives.

We attempted to eliminate this bias by defining stringent inclusion and exclusion criteria, and when in doubt we included the article.

We have defined stringent criteria for automatic inclusion of data from external sources, with the goal of limiting the inclusion of unreliable data or information that we deem of limited utility to our target audience.

Standardisation of methods used to store paraffin-embedded tumour tissue and perform IHC analysis, the use of tumour tissue obtained in clinical trials with clearly defined end points and clearly defined, stringent, inclusion criteria, may further elucidate the prognostic impact of p53 immunostaining in the future.

The samples included were from confirmed scrub typhus cases (n = 21) meeting any of the previously defined stringent STIC, i.e., culture positivity and/or an admission IgM antibody titer of >1 12,800 and/or a ≥4-fold rising IgM IFA antibody titer and/or positivity for two or more of three PCR gene targets.

Genotype phenotype associations significant at the defined stringent thresholds are summarised in figures 1– 3 and table 3. A complete list of p values significant at p<0.05 for all pairs of traits/genes is provided in table 4 for non-SP genes and online supplementary table S2 for SP and related genes.

To evaluate the distribution of fox SNPs among known coding and non-coding regions we selected 100 random SNPs that passed defined stringent filtering parameters (see method section) and localized these SNPs in the dog genome (CanFam2) using the UCSC genome browser.